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IDEC-132 shows strong antitumor activities against solid tumours. And it shows much stronger topoisomerase I inhibitory activity than topotecan and irinotecan. It is proved to be potent cytotoxic agents by inhibiting cellular DNA topoisomerase I by a mech

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Title of Journal : Bioorganic & Medicinal Chemistry  Author : Vandana Srivastava  C_Author : Arvind Singh Negi  Year : 2005  Volume No. : 13  Issue No. :   Page No. : 5892-5908  

UAS,Bengaluru Language : English
Article rating from 0 people star ratingstar ratingstar ratingstar ratingstar rating Submission Date :2012-10-01
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Solid Tumors

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